Hepatitis B vaccination in London — standard or accelerated
Hepatitis B is a viral liver infection transmitted through blood and bodily fluids. Without vaccination, chronic infection can lead to liver cirrhosis and liver cancer. The vaccine is one of the most effective in modern medicine — a completed three-dose course gives durable protection in over 95% of healthy adults.
At City Of London Clinic we plan the full course at the first appointment and book follow-up doses before you leave. Every appointment is led by Asad Repon, a GPhC-registered Independent Prescriber. Same-day first doses are routinely available with two hours' notice.
Who should consider Hepatitis B vaccination
- Healthcare workers — routine NHS vaccination, often required by employers; we can administer if your NHS course is incomplete or you need an antibody check.
- Expat employees and relocations — longer stays in high-prevalence regions (sub-Saharan Africa, East and South-East Asia, parts of Latin America, the Middle East). See our expat employee guide for the full pre-departure picture.
- Longer travel — anyone staying months rather than weeks in a high-prevalence region.
- Partner risk — if your partner is Hep B-positive.
- Aid and volunteer work involving potential bodily-fluid exposure.
- Travel involving medical or dental work abroad — medical tourism, sports injuries, etc.
The schedule — standard vs accelerated
Two main schedules:
- Standard: 0, 1 and 6 months. Best when you have at least 6 months before departure or extended stay.
- Accelerated: 0, 7 and 21 days, with a booster at 12 months. Designed for travellers with less time. Initial protection at 21 days; the 12-month booster gives long-term protection.
We book the full course at your first appointment so you don't have to chase reminders.
Combined Hepatitis A + B (Twinrix)
If you also need Hep A protection (most non-Western destinations), Twinrix is a combination vaccine that covers both. Same three-dose schedule, one injection instead of two per visit. Fewer needles, same outcome. Particularly relevant for India and Pakistan travellers who often need both.
Antibody checks for healthcare workers
NHS guidance recommends an antibody (anti-HBs) check 8-12 weeks after course completion for healthcare workers. We can arrange this through our blood testing service or refer you to your occupational health team. Most fully-vaccinated healthy adults reach a protective antibody level (>10 mIU/mL).
Side effects
Mild soreness, redness or swelling at the injection site is common. Some people experience mild fatigue or low-grade fever for 24-48 hours. Serious reactions are rare. We discuss what to expect and when to seek advice.
For HR mobility teams
For employers relocating staff to high-prevalence regions, Hepatitis B is part of standard pre-departure preparation. We work with HR mobility teams on corporate accounts — monthly invoicing, VAT receipts, dedicated billing contact, and records issued in a format compatible with your global mobility documentation requirements. For relocations to sub-Saharan Africa, Hep B is often combined with Yellow Fever and Rabies pre-exposure.
How to book
Call 020 7253 9691 or visit cityoflondonclinic.co.uk/booking. Same-day first doses routinely available with 2 hours' notice. We're at 36 Goswell Rd., Golden Lane Estate, London EC1M 7AA — 4 minutes from Barbican station.
